CNIO-CaixaResearch Frontiers Meeting: Molecular Chaperones in Cancer and Protein Quality Control

Molecular chaperones play a crucial role in maintaining protein folding, stability, and function in both normal and disease states, including cancer. Despite significant advances, our understanding of the precise molecular mechanisms underlying chaperone function and their role in cancer development remains incomplete. This conference will focus on recent progress in elucidating the structure and function of molecular chaperones, particularly HSP90, using model organisms. Additionally, we will explore the role of chaperones in networks with other proteins in cancer phenotypes, how chaperones support cancer evolution, and approaches to better target chaperones for cancer treatment. By bringing together researchers and clinicians from diverse disciplines, we aim to foster collaboration and advance our understanding of the critical role of chaperones in cancer biology.

Topics to be covered:

• Folding, misfolding, and aggregation.
• UPR and stress mechanisms
• Prefoldins and chaperones in cancer
• Targeting chaperones: chaperonotherapy

FECHA LÍMITE DE INSCRIPCIÓN 27/05/2024
FECHA LÍMITE DE ENVÍO DE RESUMEN 06/05/2024
PRECIO 200 Euro Students and CNIO staff; 400 Euro Post-docs and Academia; 600 Euro Industry.