CNIO-CaixaResearch Frontiers Meeting: Molecular Chaperones in Cancer and Protein Quality Control

CNIO-CaixaResearch Frontiers Meeting: Molecular Chaperones in Cancer and Protein Quality Control

CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS - CNIO Auditorio - Madrid - España

CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS - CNIO y FUNDACIÓN LA CAIXA

Gabriela Chiosis, Memorial Sloan Kettering Institute, US
Nabil Djouder, Spanish National Cancer Research Centre-CNIO, Spain
Judith Frydman, Stanford University, US
Óscar Llorca, Spanish National Cancer Research Centre-CNIO, Spain
Paul Workman, Centre for Cancer Drug Discovery, The Institute of Cancer Research, London, UK

Speakers:
Udai Banerji, The Institute of Cancer Research; The Royal Marsden NHS Foundation Trust, UK
Jeffrey L. Brodsky, University of Pittsburgh, Kenneth P. Dietrich School of Arts and Sciences, US
Johannes Buchner, Technical University of Munich, Germany
Benoit Coulombe, Institut de Recherches Cliniques de Montréal, Canada
Chengkai Dai, Center for Cancer Research, National Cancer Institute, US
Elke Deuerling, Konstanz University, Germany
Lila Gierasch, University of Massachusetts Amherst, US
Manajit Hayer-Hartl, Max-Planck-Institute of Biochemistry, Germany
Walid Houry, Biochemistry, University of Toronto, Canada
Ursula Jakob, University of Michigan, US
Matthias Mayer, Center for Molecular Biology Heidelberg – ZMBH, Germany
Leonard Neckers, Center for Cancer Research, National Cancer Institute, US
Rahul Samant, Babraham Institute, US
Ritwick Sawarkar, University of Cambridge, UK
Lea Sistonen, Turku Centre for Biotechnology, Finland
Peter Walter, Howard Hughes Medical Institute, University of California, US

CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS

917 328 000

eventos@cnio.es

https://www.cnio.es/eventos/molecular-chaperones-in-cancer-and-protein-quality-control/

Molecular chaperones play a crucial role in maintaining protein folding, stability, and function in both normal and disease states, including cancer. Despite significant advances, our understanding of the precise molecular mechanisms underlying chaperone function and their role in cancer development remains incomplete. This conference will focus on recent progress in elucidating the structure and function of molecular chaperones, particularly HSP90, using model organisms. Additionally, we will explore the role of chaperones in networks with other proteins in cancer phenotypes, how chaperones support cancer evolution, and approaches to better target chaperones for cancer treatment. By bringing together researchers and clinicians from diverse disciplines, we aim to foster collaboration and advance our understanding of the critical role of chaperones in cancer biology.

Topics to be covered:

• Folding, misfolding, and aggregation.
• UPR and stress mechanisms
• Prefoldins and chaperones in cancer
• Targeting chaperones: chaperonotherapy

FECHA LÍMITE DE INSCRIPCIÓN 27/05/2024
FECHA LÍMITE DE ENVÍO DE RESUMEN 06/05/2024
PRECIO 200 Euro Students and CNIO staff; 400 Euro Post-docs and Academia; 600 Euro Industry.